Name: My Friend's Little Sister Has It In for Me!
Genre: 現代, 校園, 日常, 後宮/戀愛喜劇, 喜劇
Released: 2025

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PremiereAutumn 2025

Original Work (Author)Ghost Mikawa

DirectorKazuomi Koga

Series CompositionTouko Machida

Character DesignKatsuyuki Satou

MusicHanae Nakamura

Episodes12 Episodes

Animation StudioBLADE

Opening Theme (OP)ウザ可愛くて何が悪い！ - 赤見かるび

Ending Theme (ED)星の鼓動 - こはならむ

My Friend's Little Sister Has It In for Me! is a TV anime adaptation of the light novel series by author Mikawagoost, blending school life, slice-of-life charm, and harem romantic comedy into one irresistible package. Produced by BLADE, directed by Kazuomi Koga, and with series composition handled by Deko Machida, the series brings characters like Akiteru Ooboshi, Iroha Kohinata, and Mashiro Tsukinomori to life in a modern school setting packed with humor and heart.

My Friend's Little Sister Has It In for Me! centers on Akiteru Ooboshi, a high school student who has made up his mind that youth is simply not worth the trouble. Romance, socializing, and all the drama that comes with adolescence? He wants no part of it. His days are carefully kept free of such distractions—until his best friend's younger sister, Iroha Kohinata, barges into his life uninvited. For reasons he cannot begin to fathom, Iroha reserves a uniquely relentless brand of teasing exclusively for Akiteru. She makes herself at home in his room, sprawls across his bed, and clings to him like an unstoppable force of nature. Nobody else seems to get this treatment from her—so why is he the only one she targets? With his carefully constructed peace constantly under siege, Akiteru must contend with this baffling one-sided storm of attention.

My Friend's Little Sister Has It In for Me!

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