Isha

Within the dystopian world of Akudama Drive, this brilliant physician carries a staggering 432-year sentence—a testament to the sheer scale of her crimes. Beneath her poised and refined exterior lies a profoundly warped intellect that treats human lives as mere experimental material. Mastering both surgical precision and chemical expertise, she even possesses a near-supernatural capacity for self-regeneration. Her sole ambition is absolute dominion over life and death, and the pursuit of immortality drives her to betray allies without a moment's hesitation or remorse.